Identification and characterization of the diuretic hormone 31 receptor in the silkworm Bombyx mori |
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| Authors: | Masatoshi Iga |
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| Affiliation: | Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan |
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| Abstract: | The receptor for diuretic hormone 31 (DH31R) was identified in the silkworm Bombyx mori. A heterologous expression system revealed that an orphan G-protein coupled receptor, BNGR-B1, responded to DH31 and upregulated the intracellular cAMP level. DH31R (BNGR-B1) was predominantly expressed in the anterior silk gland, midgut, and ovary, whereas DH31 was predominantly expressed in the central nervous system and midgut. |
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| Keywords: | diuretic hormone 31 G-protein coupled receptor cAMP Bombyx mori |
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