Effects of low molecular weight soybean peptide on mRNA and protein expression levels of differentiation markers in normal human epidermal keratinocytes |
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| Authors: | Yoshihiro Tokudome Kyosuke Nakamura Fumie Hashimoto |
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| Institution: | 1. Laboratory of Dermatological Physiology, Faculty of Pharmaceutical Sciences, Josai University, Sakado, Japantokudome@josai.ac.jp;3. Laboratory of Dermatological Physiology, Faculty of Pharmaceutical Sciences, Josai University, Sakado, Japan |
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| Abstract: | Low molecular weight soybean peptide (LSP) was applied to normal human epidermal keratinocytes, and the results showed a significant increase in the gene expression levels of involucrin, transglutaminase, and profilaggrin. Filaggrin protein levels were also significantly higher. It is possible that LSP has an epidermal cell differentiation-promoting effect and may be able to regulate metabolism of the epidermis. |
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| Keywords: | low molecular weight soybean peptide keratinocyte differentiation skin epidermis |
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