Practical application of flavonoid-poor menu meals to the study of the bioavailability of bilberry anthocyanins in human subjects |
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| Authors: | Hiroyuki Sakakibara Yoko Ichikawa Sanae Tajima Yoshie Makino Yusuke Wakasugi Kayoko Shimoi |
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| Institution: | 1. Faculty of Agriculture, University of Miyazaki, Miyazaki, Japanhiroyuki@cc.miyazaki-u.ac.jp;3. Graduate School of Integrated Pharmaceutical and Nutritional Sciences, University of Shizuoka, Shizuoka, Japan;4. Global COE Program, University of Shizuoka, Shizuoka, Japan;5. Graduate School of Nutritional and Environmental Sciences, University of Shizuoka, Shizuoka, Japan;6. Global COE Program, University of Shizuoka, Shizuoka, Japan |
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| Abstract: | Practical application of flavonoid-poor menus was evaluated on the bioavailability of anthocyanins as model flavonoids. Detectable amounts of flavonoids were not found in plasma and urine collected from 13 participants, who took the menus. After ingesting bilberry anthocyanins (919 μmol), average plasma AUC0-6h, Cmax, Tmax values and urinary recovery were 386.0 nmol h/mL, 139.1 nM, 1.31 h and 0.21%, respectively. |
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| Keywords: | bioavailability bilberry anthocyanins dietary reference intake flavonoid-poor menu meals human study |
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