Circadian rhythm of active amino acid transport in rat liver

Abstract

The circadian change of the encephalic photosensitivity of quail has been demonstrated. In this study the diurnal variation of the retinal photosensitivity was investigated by the electroretinogram (ERG) to explore the phase relation between the retinal and encephalic systems. The b‐wave, a major component of the ERG, was used as a measure of retinal photosensitivity.

1. In the bird maintained in LD12:12 the b‐wave amplitude of the ERG stayed at a high level for the first 10 h of the light period, and decreased abruptly around the time of light‐off. The decreased level continued until midnight. Thenceforth the b‐wave amplitude recovered progressively to the daytime level before the time of next light on.

2. In the bird maintained in LD16:8, the decrease of the retinal sensitivity in the light phase was initiated prior to the time of expected light‐off, and the onset time of decreasing tendency was advanced by 2 h, with dark adaptation for 30 min given immediately before the ERG measurement. Upon continuous light exposure, the b‐wave amplitude always remained at low level.

3. Periodic changes in retinal sensitivity persisted when the environmental dark phase was temporarily extended for 19 to 30 h.

These observations suggest that the diurnal rhythm of the neural retina in quail might be generated endogenously and appears to control the encephalic photosensitive system.