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DNA marker mining of ILSTS035 microsatellite locus on chromosome 6 of Hanwoo cattle |
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| Authors: | Jung-Sou Yeo Jea-Young Lee Jae-Woo Kim |
| Institution: | (1) Department of Animal Science, Yeungnam University, Gyeongsan, 712-749 Gyeongbuk, Korea;(2) Institute of Biotechnology, Yeungnam University, Gyeongsan, 712-749 Gyeongbuk, Korea;(3) Department of Statistics, Yeungnam University, Gyeongsan, 712-749 Gyeongbuk, Korea |
| Abstract: | We describe tests for detecting and locating quantitative trait loci (QTL) for traits in Hanwoo cattle. From results of a permutation test to detect QTL for marbling, we selected the microsatellite locus ILSTS035 on chromosome 6 for further analysis. K-means clustering analysis applied to five traits and nine DNA markers in ILSTS035 resulted in three cluster groups. Finally we employed the bootstrap test method to calculate confidence intervals using the resampling method to find major DNA markers. We conclude that the major markers of ILSTS035 locus on chromosome 6 of Hanwoo cattle are markers 235 bp and 266 bp. |
| Keywords: | LOD score QTL permutation test K-means clustering bootstrap method |
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