A hybrid blob-slice model for accurate and efficient detection of fluorescence labeled nuclei in 3D |
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Authors: | Anthony Santella Zhuo Du Sonja Nowotschin Anna-Katerina Hadjantonakis Zhirong Bao |
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Affiliation: | 1.Developmental Biology,Sloan-Kettering Institute,New York,USA |
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Abstract: | Background To exploit the flood of data from advances in high throughput imaging of optically sectioned nuclei, image analysis methods need to correctly detect thousands of nuclei, ideally in real time. Variability in nuclear appearance and undersampled volumetric data make this a challenge. |
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