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Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy |
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| Authors: | James A. McCubrey,Melissa L. Sokolosky,Jackson R. Taylor,William H. Chappell,Kristin M. Stadelman,Negin Misaghian,Jö rg Bä secke,Franca Stivala,Agostino Tafuri,Marek Zarzycki,Francesca Chiarini,Alberto M. Martelli,Richard A. Franklin |
| Affiliation: | a Department of Microbiology and Immunology, Brody School of Medicine at East Carolina University, Greenville, NC 27858, USA b Division of Hematology and Oncology, Department of Medicine, Göttingen, Germany c University of Catania, Catania, Italy d Centro di Riferimento Oncologico, Italian National Cancer Institute, Aviano, Italy e Department of Hematology-Oncology, La Sapienza, University of Rome, Rome, Italy f Regina Elena Cancer Center, Rome, Italy g University of Wroclaw, Wroclaw, Poland h University of Bologna, Bologna, Italy |
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