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Genetic deletion of monoacylglycerol lipase leads to impaired cannabinoid receptor CB1R signaling and anxiety‐like behavior
Authors:Roberta Imperatore  Giovanna Morello  Livio Luongo  Ulrike Taschler  Rosaria Romano  Danilo De Gregorio  Carmela Belardo  Sabatino Maione  Vincenzo Di Marzo  Luigia Cristino
Affiliation:1. Endocannabinoid Research Group, Institute of Biomolecular Chemistry, Consiglio Nazionale delle Ricerche, Pozzuoli, Italy;2. Department of Neurological and Movement Sciences, University of Verona, Verona, Italy;3. Endocannabinoid Research Group, Department of Experimental Medicine, Division of Pharmacology “L. Donatelli”, Second University of Naples, Naples, Italy;4. Institute of Molecular Biosciences, University of Graz, Graz, Austria
Abstract:
Keywords:2‐arachidonoylglycerol (2‐AG)  anxiety‐like behavior  CB1R  endocannabinoids  MAGL‐KO mice  synaptic plasticity
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