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Role of platinum DNA damage‐induced transcriptional inhibition in chemotherapy‐induced neuronal atrophy and peripheral neurotoxicity
Authors:Fang Yan  Johnson J Liu  Virginia Ip  Stephen M F Jamieson  Mark J McKeage
Affiliation:1. Department of Pharmacology and Clinical Pharmacology, School of Medical Sciences, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand;2. School of Medicine, Faculty of Health, University of Tasmania, Hobart, Tasmania, Australia;3. Auckland Cancer Society Research Centre, School of Medical Sciences, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand
Abstract:
Keywords:anticancer drug toxicity  DNA damage  DRG neurons  global transcription  neuronal atrophy  neurotoxicity
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