Identification of collagen alpha1(I) trimer in embryonic chick tendons and calvaria |
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Authors: | S A Jimenez R I Bashey M Benditt R Yankowski |
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Institution: | Milton Benditt and Ronald Yankowski Department of Medicine, School of Medicine, University of Pennsylvania. 3700 Hamilton Walk, Philadelphia, Pennsylvania 19174 U.S.A. |
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Abstract: | Collagen with a molecular composition α1(I)]3 has been identified in acetic acid extracts from lathyritic chick embryo tendons and calvaria. These molecules characteristically have greater solubility than Type I collagen at neutral pH and contain increased amounts of hydroxylysine residues. It is suggested that these molecules represent a separate gene product of embryonic cells which may be important in the process of maturation and development. |
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Keywords: | To whom correspondence should be addressed |
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