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Novel pyrazolopiperazinone- and pyrrolopiperazinone-based MCH-R1 antagonists |
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| Authors: | Meyers Kenneth M Méndez-Andino José Colson Anny-Odile Hu X Eric Wos John A Mitchell Maria C Hodge Karen Howard Jeremy Paris Jennifer L Dowty Martin E Obringer Cindy M Reizes Ofer |
| Institution: | Procter and Gamble Pharmaceuticals, 8700 Mason-Montgomery Road, Mason, OH 45039, USA. |
| Abstract: | The synthesis and biological testing of novel classes of potent melanin-concentrating hormone (MCH-R1) antagonists based on pyrazolopiperazinone and pyrrolopiperazinone scaffolds are described. |
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