The role of natural killer T cells and other T cell subsets against infection by the pre-erythrocytic stages of malaria parasites |
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| Authors: | Schmieg John Gonzalez-Aseguinolaza Gloria Tsuji Moriya |
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| Affiliation: | Department of Medical and Molecular Parasitology, New York University School of Medicine, 341 East 25th Street, New York, NY 10010, USA. |
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| Abstract: | T cells are critical mediators of immunity to the pre-erythrocytic stages of malaria parasites. In this review, we survey the role of the various T cell subsets in combating the pre-erythrocytic stages; in particular, the role of NK T cells. Moreover, we show how studies using malaria models have revealed a unique behavior of NK T cells, namely the bridging of innate and adaptive immunity. |
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