External ecological niche for Candida albicans within reducing, oxygen-limited zones of wetlands |
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Authors: | Stone Wendy Jones Barbara-Lee Wilsenach Jac Botha Alfred |
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Institution: | Department of Microbiology, Stellenbosch University, Stellenbosch, South Africa. |
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Abstract: | Candida albicans within the human host is well studied; however, identifying environmental reservoirs of pathogens is epidemiologically valuable for disease management. Oxygen-limited, carbohydrate-rich zones of wetlands, to which sewage-borne C. albicans is often exposed, are characteristically similar to the gastrointestinal reservoir. Consequently, using quantitative real-time PCR (qRT-PCR) and gas chromatography-mass spectrometry (GC-MS), we demonstrated that oxygen-limited zones in polluted wetlands may act as potential reservoirs of C. albicans. |
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