The release of iron from horse spleen ferritin to 1,10-phenanthroline |
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| Authors: | Terence G. Hoy Pauline M. Harrison Mohammad Shabbir Ian G. Macara |
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| Affiliation: | Department of Biochemistry, University of Sheffield, Sheffield S10 2TN, U.K. |
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| Abstract: | The rate of release of iron to 1,10-phenanthroline from ferritin fractions of different iron contents has been studied. The experimental results could be interpreted by a simple hypothetical model of the shape of the hydrous ferric oxide micelle at different iron contents, and reasonable correlation obtained between the rate of release and the calculated micelle surface areas. Initial rates of release did not correlate significantly with protein concentration. |
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