4-O[(S)-1-carboxyethyl]-D-glucuronic acid: a component of the Klebsiella type 37 capsular polysaccharide |
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Authors: | Bengt Lindberg Bengt Lindberg Jörgen Lönngren Wolfgang Nimmich |
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Affiliation: | Department of Organic Chemistry, Arrhenius Laboratory, University of Stockholm, S-104 05 Stockholm Sweden;Institut für Medizinische Mikrobiologie und Epidemiologie der Universität Rostock, DDR-25 Rostock 1 German Democratic Republic |
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Abstract: | The acidic sugar component in the Klebsiella type 37 capsular polysaccharide (K 37) has been identified as 4-O-[(S)-1-carboxyethyl]-D-glucuronic acid. The identification is based upon chemical and spectroscopic studies, and the identity of the carboxyl-reduced sugar, 4-O-[(S)-2-(1-hydroxy)propyl]-D-glucose and derivatives, with the corresponding substances synthesized by an unambiguous route. |
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