Further study of the structure of lentinan,an anti-tumor polysaccharide from Lentinus edodes |
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Authors: | Takuma Sasaki Nobuo Takasuka |
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Institution: | National Cancer Center Research Institute, Tsukiji 5-1-1, Chuo-ku, Tokyo Japan |
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Abstract: | The structure of lentinan, an anti-tumor polysaccharide from Lentinus edodes, has been further investigated. Periodate oxidation, Smith degradation, methylation analysis, and bioassay were the principal methods used. These studies showed that a branched molecule having a backbone of (1→3)-β-d-glucan and side chains of both β-d-(1→3)- and β-d-(1→6)-linked d-glucose residues, together with a few internal β-d-(1→6)-linkages, is present. |
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