Detection of human genetic linkage: foundations |
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| Authors: | Thompson E |
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| Affiliation: | Department of Statistics, University of Washington, Seattle, Washington 98195, USA. |
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| Abstract: | Starting with the basics of inheritance, recombination, and genetic map distance, we develop the theory of linkage analysis considering data on an individual or on a sib pair, with and without data on parents. We discuss the effects of ascertainment of individuals with certain traits and the effects of allelic associations between a trait and a linked marker locus. |
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