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Protective activity of adsorbed D(a)PT vaccine with the acellular pertussis component and polyoxydonium |
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| Authors: | Zakharova N S Britsina M V Ozeretskovskaia M N Bazhanova I G Mertsalova N U Poddubikov A V Zaĭtsev E M Ermolova E V |
| Abstract: | The introduction of the immunomodulator polyoxidonium in an amount of 0.5 Mg/ml into adsorbed D(a)PT vaccine with the acellular pertussis component leads to the preservation of the protective activity of the pertusis component, diphtheria and tetanus toxoids, as well to the 4-time decrease of the content of adsorbent (aluminium hydroxide) from 2 to 0.5 mg/ml. |
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