(1) Division of Biological Sciences, The University of Michigan, 48109 Ann Arbor, Michigan, USA;(2) Department of Genetics, University of Dublin, Trinity College, Dublin 2, Ireland
Abstract:
The resistance of exponentially growing yeast cells to killing by exposure to 52°C increased markedly as the growth temperature was increased. Identical killing curves were obtained for cells suspended in growth medium or in 0.9% saline. Cells resistant to killing at 52°C were quite sensitive to killing at slightly higher temperatures. These results suggest a primary role for membrane damage in the mechanism of heat killing.