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Effect of growth temperature upon heat sensitivity in Saccharomyces cerevisiae |
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| Authors: | E Fintan Walton John R Pringle |
| Institution: | (1) Division of Biological Sciences, The University of Michigan, 48109 Ann Arbor, Michigan, USA;(2) Department of Genetics, University of Dublin, Trinity College, Dublin 2, Ireland |
| Abstract: | The resistance of exponentially growing yeast cells to killing by exposure to 52°C increased markedly as the growth temperature was increased. Identical killing curves were obtained for cells suspended in growth medium or in 0.9% saline. Cells resistant to killing at 52°C were quite sensitive to killing at slightly higher temperatures. These results suggest a primary role for membrane damage in the mechanism of heat killing. |
| Keywords: | Yeast Saccharomyces cerevisiae Heat killing Membrane damage Genetic damage Growth temperature |
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