Localization of the human GLO gene locus |
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Authors: | B. Olaisen T. Gedde-Dahl Jr. E. Thorsby |
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Affiliation: | (1) University Institute of Forensic Medicine, University of Oslo, Oslo;(2) Genetics Laboratory, Norsk Hydro's Institute for Cancer Research, Radiumhospitalet, Oslo;(3) Tissue Typing Laboratory, Rikshospitalet, Oslo;(4) Rettsmedisinsk Institutt, Rikshospitalet, Oslo 1, Norway |
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Abstract: | Summary Data on the linkage relation between the GLO locus and the HLA, Bf, and PGM3 loci are presented. The family material includes 49 GLO/HLA-B (and/or Bf) segregating matings with 134 children informative on 199 parental meioses. Of phase-known meioses, 3 are recombinants and 75 nonrecombinants; linkage is therefore proven. From the total material a distance of 2.5 cM between GLO and HLA-B/Bf is calculated; and from the segregation in some informative family groups it is shown that GLO is situated between PGM3 and HLA-B/Bf. |
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