Genetic variation of phosphoglucose isomerase in some hystricomorph rodents |
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| Authors: | Nicholas D Carter Michael R Hill Barbara J Weir |
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| Institution: | (1) Department of Biochemistry, The London Hospital Medical College, University of London, London, England;(2) Wellcome Institute of Comparative Physiology, Zoological Society of London, London, England |
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| Abstract: | Phosphoglucose isomerase electrophoretic variation has been studied in hystricomorph rodents. Intraspecies variation was found in chinchilla (Chinchilla laniger) and cuis (Galea musteloides). Interspecies hybridization of Cavia aperea and Cavia porcellus was found to produce hybrid enzymes. In all cases, breeding data indicated an autosomal mode of inheritance, while electrophoretic patterns were consistent with a dimeric structure for the enzyme. Possible evolutionary relationships of phosphoglucose isomerase with respect to taxonomy are discussed.The laboratory studies were supported by the Royal Society and Agricultural Research Council (N. D. C. and M. R. H.) and the Ford Foundation (B. J. W.). |
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