1. Biotech Research and Innovation Centre, University of Copenhagen, Ole Maaløes Vej 5, 2200 Copenhagen, Denmark;2. Centre for Epigenetics, University of Copenhagen, Ole Maaløes Vej 5, 2200 Copenhagen, Denmark;3. The Bioinformatics Centre, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, 2200 Copenhagen, Denmark
Abstract:
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Highlights? Fbxl10 binds to most CpG islands in ESCs ? Fbxl10 recruits Nspc1 and Ring1B to CpG islands ? The Fbxl10, Nspc1, and Ring1B complex is required for H2A monoubiquitylation ? Fbxl10 is required for proper ESC differentiation
