Role of plasma ANG II in the excretion of acute sodium load in a bird with salt glands (Anas platyrhynchos) |
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Authors: | Heinz M K Gray D A |
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Affiliation: | Department of Physiology, University of the Witwatersrand, Johannesburg 2050, South Africa. myriamh@twrinet.twr.ac.za |
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Abstract: | This study was designed to further examine the role of plasma ANG II in the excretion of sodium in the Pekin duck, a bird with salt glands. Renal and extrarenal (salt gland) excretion of an intravenously administered isotonic saline load was monitored over a 4-h period in a group of eight birds under two conditions: the control condition, in which isotonic saline infusion decreased endogenous plasma ANG II from 102.6 to 16.5 pg/ml, and the experimental condition, in which ANG II suppression was prevented by intravenous infusion of a 3.5 ng. kg(-1). min(-1) dose of synthetic ANG II. ANG II infusion significantly decreased the total sodium excretion (by 15%), primarily via an inhibition of salt gland output. The results suggest that ANG II suppression facilitates the excretion of an administered sodium load in birds with salt glands. |
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