Metabolism of glucose, trehalose, citrate, acetate, and palmitate by the male desert locust during adult development |
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| Authors: | P R Walker E Bailey |
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| Affiliation: | 1. Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Takamatsu, Kagawa 761-0395, Japan;2. Hayashibara Co., Ltd., Naka-ku, Okayama 702-8006, Japan;1. Department of life sciences, Laboratory of Biodiversity and Aquatic Ecosystems, Ecology and plankktonology, University of Sfax Tunisia, Faculty of Sciences, Unit UR 11 ES 72/Street of Soukra Km 3,5, B.P. 1171, CP 3000 Sfax, Tunisia;2. University of Sfax Tunisia, Faculty of Sciences, Department of life sciences, Laboratory of Animal Ecophysiology, B.P. 95, 3000, Tunisia;1. Department of Biochemistry, McMaster University, 1280 Main St W, Hamilton, ON L8S 4L8, Canada;2. Department of Medicine, Division of Nephrology, McMaster University, St. Joseph''s Healthcare Hamilton, 50 Charlton Ave E, Hamilton, ON L8N 4A6, Canada;1. College of Animal Science and Veterinary Medicine, Shandong Agricultural University, 61 Daizong Street, Tai''an City, Shandong Province, 271018, China;2. Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong Agricultural University, 61 Daizong Street, Tai''an City, Shandong Province, 271018, China;3. Shandong Provincial Engineering Technology Research Center of Animal Disease Control and Prevention, Shandong Agricultural University, 61 Daizong Street, Tai''an City, Shandong Province, 271018, China;1. Department of Pathology and Laboratory Medicine, UTHealth McGovern Medical School, Houston, Texas;2. The University of Texas MD Anderson Cancer Center, UTHealth Graduate School of Biomedical Sciences, Houston, Texas;1. Center for Cardiovascular Research and Alternative Medicine, University of Wyoming College of Health Sciences, Laramie, WY 82071, USA;2. Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai 200032, China |
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| Abstract: | The ability of the fat body to synthesize lipid during development of the adult male desert locust has been investigated by following the rates of incorporation of labelled glucose, trehalose, acetate, and citrate into fat body lipid. There is a small increase in lipogenesis during the first 3 days of adult life, but the major period of lipogenesis occurs between day 5 and day 7. The mature insect then maintains a relatively high capacity for lipogenesis. The patterns of glucose and trehalose incorporation into lipid are similar to that of acetate, thus the insect has the capacity to convert carbohydrate to lipid during development. Citrate incorporation parallels the acetate incorporation and is thought to be an important intermediate in the conversion of carbohydrate to lipid in the locust. The amounts of these metabolites oxidized for energy production in relation to the amounts converted to lipid during development was also investigated.The capacity of the fat body for lipid oxidation during development was investigated by following the rate of breakdown of labelled palmitate to acid soluble material and CO2. The ability to oxidize lipid is low during the first 6 days of adult life, then increases rapidly between day 6 and day 8, and remains at a high level until 14 days.From these results it is clear that the fat body synthesizes lipid during the first 7 days of adult life and subsequently oxidizes this accumulated lipid. These overall changes in metabolism can be correlated with the changes in the lipid content of the fat body and changes in the activities of enzymes associated with lipogenesis measured in previous work.The ability of flight muscle to oxidize both lipid and carbohydrate for energy production was also investigated by measuring the rate of oxidation of labelled trehalose and palmitate by this tissue. It was found that flight muscle has the capacity to oxidize both lipid and carbohydrate at all stages of development. |
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