Testing equality of survival functions of quality-adjusted lifetime |
| |
Authors: | Zhao H Tsiatis A A |
| |
Institution: | Department of Statistics, North Carolina State University, Raleigh, 27695, USA. zhao@bst.rochester.edu |
| |
Abstract: | We present a method for comparing the survival functions of quality-adjusted lifetime from two treatments. This test statistic becomes the ordinary log-rank test when quality-adjusted lifetime is the same as the survival time. Simulation experiments are conducted to examine the behavior of our proposed test statistic under both null and alternative hypotheses. In addition, we apply our method to a breast cancer trial for comparing the distribution of quality-adjusted lifetime between two treatment regimes. |
| |
Keywords: | Counting processes Hypothesis test Martingale processes Quality of life Survival analysis |
本文献已被 PubMed 等数据库收录! |
|