Voltage Clamp Experiments on Single Muscle Fibers of Rana pipiens |
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Authors: | L. E. Moore |
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Affiliation: | From the Department of Physiology, Case Western Reserve University, Cleveland, Ohio 44106 |
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Abstract: | A voltage clamp for single muscle fibers has been developed. Stability of the system was achieved when an artificial node was created by enclosing a single muscle fiber in a petroleum jelly seal which served as an analogue of the myelin sheath. Typical voltage clamp records were obtained with large inward transient currents followed by a delayed rectification of the outward currents. These currents looked qualitatively similar when the transverse tubular system was destroyed. Errors in current measurement, especially those due to anomalous rectification, are discussed. |
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