Myosin learns to recruit AMPA receptors |
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Authors: | Perlson Eran Holzbaur Erika L F |
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Affiliation: | Department of Physiology, University of Pennsylvania School of Medicine, D400 Richards Building, 3700 Hamilton Walk, Philadelphia, PA, 19104-6085, USA. |
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Abstract: | The induction of long-term potentiation (LTP) leads to an increase in the density of AMPA receptors at dendritic spines. New work by Wang et al. (2008) reveals the mechanism by which myosin Vb regulates the intracellular trafficking of AMPA receptors from recycling endosomes to synaptic sites during LTP. |
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