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玛咖醇提物对正常小鼠免疫功能的影响
引用本文:张永忠,余龙江,万军梅,金文闻. 玛咖醇提物对正常小鼠免疫功能的影响[J]. 天然产物研究与开发, 2007, 19(2): 274-276
作者姓名:张永忠  余龙江  万军梅  金文闻
作者单位:华中科技大学生命科学与技术学院,武汉,430074
摘    要:本文采用小鼠碳粒廓清、植物血凝素(PHA)诱导淋巴细胞转化,以及血清溶血素和抗体生成细胞测定等实验,研究南美植物玛咖的乙醇提取物对正常小鼠免疫功能的影响。结果表明,玛咖醇提物显著提高PHA诱导的淋巴细胞转化,促进血清溶血素生成,并增加抗体生成细胞的产生,而对单核巨噬细胞的吞噬功能无显著影响。因此,玛咖醇提取物可提高正常小鼠细胞和体液免疫功能,增强机体抵抗力。

关 键 词:玛咖  碳粒廓清  淋巴细胞转化  体液免疫功能
文章编号:1001-6880(2007)02-0274-03
收稿时间:2005-09-12
修稿时间:2005-11-29

Effect of Ethanol Extract of Lepidium meyenii Walp. (Maca)on Immunological Function of Mice
ZHANG Yong-zhong,YU Long-jiang,WAN Jun-mei,JIN Wen-wen. Effect of Ethanol Extract of Lepidium meyenii Walp. (Maca)on Immunological Function of Mice[J]. Natural Product Research and Development, 2007, 19(2): 274-276
Authors:ZHANG Yong-zhong  YU Long-jiang  WAN Jun-mei  JIN Wen-wen
Affiliation:School of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China
Abstract:The study was to investigate the effect of ethanol extract of Lepidium meyenii Walp.(Maca) on immunological function of mice.Determinations of clearance of carbon particles,lymphocyte transformation induced by phytohemagglutinin (PHA),hemolysin content in serum and antibody-producing cell of spleen in mice were carried out.Oral administration of ethanol extract of Maca significantly increased the rate of transformation of lymphocyte induced by PHA and it also promoted production of hemolysin in serum and antibody-producing cell in spleen.Our study suggests that ethanol extract of Maca may enhance cellular and humoral immunity function in mice.
Keywords:Lepidium meyenii Walp.(Maca)  clearance of carbon particles  transformation of lymphocyte  humoral immune function
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