Cytoplasmic dynein could be key to understanding neurodegeneration |
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| Authors: | Gareth T Banks Elizabeth MC Fisher |
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| Affiliation: | Department of Neurodegenerative Disease, Institute of Neurology, Queen Square, London WC1N 3BG, UK. g.banks@prion.ucl.ac.uk. |
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| Abstract: | A new mouse mutation, Sprawling, highlights an essential role for the dynein heavy chain in sensory neuron function, but it lacks the ability of other known heavy-chain mutations to ameliorate neurodegeneration due to defective superoxide dismutase. |
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