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Development of bone marrow lesions is associated with adverse effects on knee cartilage while resolution is associated with improvement - a potential target for prevention of knee osteoarthritis: a longitudinal study |
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| Authors: | Miranda L Davies-Tuck Anita E Wluka Andrew Forbes Yuanyuan Wang Dallas R English Graham G Giles Richard O'Sullivan Flavia M Cicuttini |
| Institution: | (1) Department of Epidemiology and Preventive Medicine, Monash University, Central and Eastern Clinical School, Alfred Hospital, Melbourne, VIC, 3004, Australia;(2) Baker Heart Research Institute, Commercial Road, Melbourne, VIC, 3004, Australia;(3) Cancer Epidemiology Centre, The Cancer Council Victoria, Carlton, VIC, 3053, Australia;(4) Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, School of Population Health, The University of Melbourne, Carlton, VIC, 3053, Australia;(5) MRI Unit, Symbion Imaging, Epworth Hospital, Richmond, VIC, 3121, Australia |
| Abstract: | IntroductionTo examine the relationship between development or resolution of bone marrow lesions (BMLs) and knee cartilage properties in a 2 year prospective study of asymptomatic middle-aged adults. |
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