BOX elements modulate gene expression in Streptococcus pneumoniae: impact on the fine-tuning of competence development |
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| Authors: | Knutsen Eivind Johnsborg Ola Quentin Yves Claverys Jean-Pierre Håvarstein Leiv Sigve |
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| Institution: | Department of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, As, Norway. |
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| Abstract: | More than 100 BOX elements are randomly distributed in intergenic regions of the pneumococcal genome. Here we demonstrate that these elements can affect expression of neighboring genes and present evidence that they are mobile. Together, our findings show that BOX elements enhance genetic diversity and genomic plasticity in Streptococcus pneumoniae. |
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