Testosterone production by rabbit testis slices |
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| Authors: | G M Connell K B Eik-Nes |
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| Affiliation: | 1. The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Qilu Hospital of Shandong University, Jinan, Shandong, China;2. Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China;3. Rehabilitation Center, Qilu Hospital of Shandong University, Jinan, Shandong, China;4. Department of Cardiology, Shandong Provincial Hospital, Shandong University, Jinan, Shandong, China;5. Department of Cardiology, Jinan Central Hospital, Shandong University, Jinan, Shandong, China;1. State Key Laboratory of Mechanical System and Vibration, School of Mechanical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, China;2. Aerospace System Engineering Shanghai, 3888 Yuanjiang Road, Shanghai 201108, China;3. Hunan Provincial Key Laboratory of Vehicle Power and Transmission System, Hunan Institute of Engineering, Xiangtan 411104, China;1. Department of Earth and Environmental Sciences, University of Milan – Bicocca, Piazza della Scienza 2, 20126 Milan, Italy;2. MaRHE Center (Marine Research and High Education Center), Magoodhoo Island, Faafu Atoll, Maldives;3. Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, 20156 Milan, Italy;4. Department of Analytical Chemistry, Faculty of Chemistry, Complutense University of Madrid, Avenida Complutense s/n, E-28040 Madrid, Spain;5. Department of Analytical Chemistry, Institute for Food Analysis and Research, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain;6. Department of Medicine and Surgery, University of Milano-Bicocca, via Cadore 48, 20052 Monza, MB, Italy;7. Department of Biotechnologies and Biosciences, University of Milan-Bicocca, Piazza della Scienza 2, 20126 Milan, Italy;1. Department of Clinical Psychological Science, Maastricht University, Maastricht, The Netherlands;2. Policlinic, Urology Unit, University of Aldo Moro, Bari, Italy;3. Escola de Psicologia e Ciências da Vida, Universidade Lusófona de Humanidades e Tecnologias, Lisbon, Portugal;4. Endocrinology Unit, Medical Department, Azienda USL, Maggiore-Bellaria Hospital, Bologna, Italy;5. Center for Health and Medical Psychology, Örebro University, Örebro, Sweden;6. Chair of Endocrinology and Medical Sexology (ENDOSEX), Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy;7. CICPSI, Faculdade de Psicologia, Universidade de Lisboa, Alameda da Universidade, Lisboa, Portugal;8. Universidade Lusófona de Humanidades e Tecnologias, Lisbon, Portugal;9. Faculdade de Psicologia e Ciências da Educação & CPUP, Universidade do Porto, Portugal;10. Flare Health, Amstelveen, The Netherlands;11. Department of Clinical Psychology, Open University, Heerlen, The Netherlands |
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| Abstract: | Testosterone production by rabbit testis slices has been studied. It has been demonstrated that interstitial cell stimulating hormone, follicle stimulating hormone, and the nucleotide, adenosine-3′,5′- monophosphate will increase the production of testosterone in this system. Theophylline, a competitive inhibitor of the phosphodiesterase enzyme, also will cause an increased production of testosterone by rabbit testis slices thus suggesting that the adenyl cyclase-phosphodiesterase system may be a functional unit in the rabbit testis. |
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