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Changing ratios of omega-6 to omega-3 fatty acids can differentially modulate polychlorinated biphenyl toxicity in endothelial cells |
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| Authors: | Wang Lei Reiterer Gudrun Toborek Michal Hennig Bernhard |
| Institution: | Graduate Center for Nutritional Sciences, University of Kentucky, Lexington 40536, USA. |
| Abstract: | |
| Keywords: | PCB polychlorinated biphenyl EC endothelial cell LA linoleic acid ALA α-linolenic acid NF-κB nuclear factor κB VCAM-1 vascular cell adhesion molecule-1 COX-2 cyclooxygenase-2 PGE2 prostaglandin E2 AhR aryl hydrocarbon receptor IL-6 interleukin 6 DCF dichlorofluorescein EMSA electrophoretic mobility shift assay MCP-1 monocyte chemoattractant protein 1 TNF-α tumor necrosis factor-alpha PDTC pyrrolidine dithiocarbamate |
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