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In vitro autoradiographic localization of vasoactive intestinal peptide (VIP) binding sites in the rat central nervous system
Authors:Jacqueline Besson  Monique Dussaillant  Jean-Claude Marie  William Rostene  Gabriel Rosselin
Affiliation:Unité de Recherches de Diabétologie et d''Etudes Radio-Immunologiques des Hormones Protéiques U.55 (INSERM), Hôpital Saint-Antoine, 184, rue du Faubourg Saint-Antoine 75571 Paris Cedex 12, France
Abstract:This paper describes the autoradiographic distribution of VIP binding sites in the rat central nervous system using monoiodinated 123I-labeled VIP. High densities of VIP binding sites are observed in the granular layer of the dorsal dentate gyrus of the hippocampus, the basolateral amygdaloid nucleus, the dorsolateral and median geniculate nuclei of the thalamus as well as in the ventral part of the hypothalamic dorsomedial nucleus.
Keywords:In vitro autoradiography  VIP  Rat central nervous system
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