In vitro autoradiographic localization of vasoactive intestinal peptide (VIP) binding sites in the rat central nervous system |
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Authors: | Jacqueline Besson Monique Dussaillant Jean-Claude Marie William Rostene Gabriel Rosselin |
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Affiliation: | Unité de Recherches de Diabétologie et d''Etudes Radio-Immunologiques des Hormones Protéiques U.55 (INSERM), Hôpital Saint-Antoine, 184, rue du Faubourg Saint-Antoine 75571 Paris Cedex 12, France |
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Abstract: | This paper describes the autoradiographic distribution of VIP binding sites in the rat central nervous system using monoiodinated 123I-labeled VIP. High densities of VIP binding sites are observed in the granular layer of the dorsal dentate gyrus of the hippocampus, the basolateral amygdaloid nucleus, the dorsolateral and median geniculate nuclei of the thalamus as well as in the ventral part of the hypothalamic dorsomedial nucleus. |
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Keywords: | In vitro autoradiography VIP Rat central nervous system |
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