Connecting extracellular metabolomic measurements to intracellular flux states in yeast |
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| Authors: | Monica L Mo Bernhard Ø Palsson Markus J Herrgård |
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| Affiliation: | (1) Department of Bioengineering, University of California, San Diego, La Jolla CA 92093, USA;(2) Synthetic Genomics, Inc, 11149 N Torrey Pines Rd, La Jolla, CA 92037, USA |
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| Abstract: | Background Metabolomics has emerged as a powerful tool in the quantitative identification of physiological and disease-induced biological states. Extracellular metabolome or metabolic profiling data, in particular, can provide an insightful view of intracellular physiological states in a noninvasive manner. |
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