| 蛋氨酸脑啡肽对免疫系统恢复作用的研究 |
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| 引用本文： | 王大南,孟静娟,吕昌龙,单风平.蛋氨酸脑啡肽对免疫系统恢复作用的研究[J].微生物学杂志,2008,28(5):39-41. |
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| 作者姓名： | 王大南 孟静娟 吕昌龙 单风平 |
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| 作者单位： | 1. 中国医科大学,免疫教研室,辽宁,沈阳,110001
2. 中国医科大学,第四附属医院药剂科,辽宁,沈阳,110032 |
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| 摘 要： | 采用固相合成法合成蛋氨酸脑啡肽,制备成注射液。对经放化疗后免疫系统受到伤害的晚期肿瘤志愿者进行治疗,经静脉滴注15 d。患者免疫系统指标全面迅速恢复,淋巴细胞亚群间比例趋于合理,证明蛋氨酸脑啡肽可以用于癌症患者的免疫系统的恢复治疗。
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| 关 键 词： | 蛋氨酸脑啡肽 免疫系统 淋巴细胞亚群 |
Immune system restore on terminal cancer patients by bio-peptide: Methionine Enkephalin(MEK) |
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| WANG Da-nan,MENG Jing-juan,LV Chang-long,SHAN Feng-ping.Immune system restore on terminal cancer patients by bio-peptide: Methionine Enkephalin(MEK)[J].Journal of Microbiology,2008,28(5):39-41. |
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| Authors: | WANG Da-nan MENG Jing-juan LV Chang-long SHAN Feng-ping |
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| Abstract: | Methionine enkephalin(MEK) is a penta peptide with broad modulating effects on immune system and known to be Th1 modulator.The aim of this work is to observe MEK's impact on subpopulation of lymphocytes in cancer patients whose immune system is damaged by chemotherapy.Infuse MEK intravenously according to protocol schedule.After treatment key immune cell parameters in patients restored to normal level and maintained,especially for CD4 /CD8 .This provides meaningful clue and potential way to maintain perfect immune system in cancer patients during treatment.Furthermore it may reveal some correlation between CD4 /CD8 and cancer developing. |
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| Keywords: | Methionine Enkephalin Immune therapy |
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