An investigation into the role of SH1 and SH2 groups of myosin in calcium binding and tension generation |
| |
| Authors: | S Srivastava J Wikman-Coffelt |
| |
| Affiliation: | Cardiovascular Research Institute, University of California, Medical Center, San Francisco, California 94143 USA |
| |
| Abstract: | Myosin heavy chains influence the Ca2+ binding properties of the light chains. When the SH1 + SH2 moieties of myosin, located on heavy meromyosin S-1, are blocked, myosin loses its Ca2+ binding capabilities. Furthermore, (SH1 + SH2)-blocked myosin no longer expresses tension when analyzed as modified actomyosin threads. When the SH1 moiety of myosin is blocked, myosin continues to express normal Ca2+ binding properties as well as normal tension. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ |
|
