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Targeting energy metabolic and oncogenic signaling pathways in triple-negative breast cancer by a novel adenosine monophosphate-activated protein kinase (AMPK) activator
Authors:Lee Kuen-Haur  Hsu En-Chi  Guh Jih-Hwa  Yang Hsiao-Ching  Wang Dasheng  Kulp Samuel K  Shapiro Charles L  Chen Ching-Shih
Institution:Division of Medicinal Chemistry, College of Pharmacy, Ohio State University, Columbus, Ohio 43210-1291, USA.
Abstract:
Keywords:Akt PKB  AMP-activated Kinase (AMPK)  Breast Cancer  Cancer Therapy  Lipogenesis  mTOR  Tumor Metabolism  IL-6  Stat3  Drug Discovery
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