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Biotinylated phosphotyrosine containing peptides: A valuable tool for studies on phosphopeptide interactions with SH2 and PTB domains |
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| Authors: | Carlos Garcí a-Echeverrí a, Christelle Stamm, Roman Wille, Dorothee Arz Brigitte Gay |
| Affiliation: | (1) Oncology Research, Novartis Pharma Inc., CH-4002 Basel, Switzerland |
| Abstract: | A series of biotinylated phosphopeptides has been synthesized and used in the development of an ELISA-based approach to assess SH2/PTB-phosphoprotein interactions in vitro in terms of affinity and specificity. |
| Keywords: | ELISA Assay Specificity Protein interactions |
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