An insect brain peptide as a member of insulin family |
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| Authors: | H Ishizaki A Suzuki |
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| Affiliation: | Biological Institute, Faculty of Science, Nagoya University, Japan. |
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| Abstract: | Amino acid sequencing of bombyxin (previously called 4K-PTTH) isolated from the heads of the silkmoth Bombyx mori has disclosed sequence homology of this insect neuropeptide with insulin. Immunohistochemistry using an antibody against a synthetic bombyxin fragment detected 4 pairs of immunoreactive neurosecretory cells in the dorso-medial region of the Bombyx brain. The same cells were reactive to bovine insulin antibody. |
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