Protective effect of liver ischemic preconditioning on rat hepatocytes |
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Authors: | JianZhu Fu Yu Wang LiJun Zhang ZeLi Yu |
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Affiliation: | Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China; Department of General Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China |
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Abstract: | Ischemic preconditioning (IPC) protects liver graft function following ischemia in liver transplantation and liver resection. The aim of this study was to assess the advantages and any potential disadvantages of liver IPC prior to isolation for rat hepatocytes during isolation and cryopreservation. After isolating and thawing the cryopreserved hepatocytes after 14 and 28 d,cell viability,efficiency,and lactate dehydrogenase (LDH) levels in preserve solution were examined for every group. Groups treated with... |
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Keywords: | liver ischemic preconditioning hepatocytes cryopreservation |
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