Effective removal of albumin from serum |
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| Authors: | Colantonio David A Dunkinson Christy Bovenkamp Diane E Van Eyk Jennifer E |
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| Affiliation: | Department of Physiology, Queen's University, Kingston, Ontario, Canada. |
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| Abstract: | The protein constituents of serum can range from grams to picograms per liter, making it technically difficult to achieve in-depth proteomic analysis. Removal of highly abundant proteins, such as albumin, coupled to powerful protein separation methods is required for increased sample load, thus facilitating detection and identification of low-abundant proteins. We report here a chemical-based extraction method for the effective and specific removal of albumin from serum. |
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