Lycoparins A-C, new alkaloids from Lycopodium casuarinoides inhibiting acetylcholinesterase |
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| Authors: | Hirasawa Yusuke Kato Eri Kobayashi Jun'ichi Kawahara Nobuo Goda Yukihiro Shiro Motoo Morita Hiroshi |
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| Institution: | Faculty of Pharmaceutical Sciences, Hoshi University, Ebara 2-4-41, Shinagawa-ku, Tokyo 142-8501, Japan. |
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| Abstract: | Three new Lycopodium alkaloids, lycoparins A-C (1-3), have been isolated from the club moss Lycopodium casuarinoides. Structures and stereochemistry of 1-3 were elucidated on the basis of 2D NMR correlations. Lycoparins C (3) exhibited an inhibitory activity against acetylcholinesterase, while lycoparins A (1) and B (2) did not show activity. |
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