Diversity of natural products of the genera Curvularia and Bipolaris |
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Authors: | Afra Khiralla Rosella Spina Sahar Saliba Dominique Laurain-Mattar |
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Affiliation: | 1. Botany Department, Faculty of Sciences and Technologies, Shendi University, P.O. Box 142, Shendi, Sudan;2. Université de Lorraine, CNRS, L2CM, F-54000, Nancy, France |
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Abstract: | Covering from 1963 to 2017.This review provides a summary of some secondary metabolites isolated from the genera Curvularia and Bipolaris from 1963 to 2017. The study has a broad objective. First to afford an overview of the structural diversity of these genera, classifying them depending on their chemical classes, highlighting individual examples of chemical structures. Also some information regarding their biological activities are presented. Several of the compounds reported here were isolated exclusively from endophytic and pathogenic strains in culture, while few from other sources such as sea Anemone and fish. Some secondary metabolites of the genus Curvularia and Bipolaris revealed a fascinating biological activities included: anti-malarial, anti-biofouling, anti-larval, anti-inflammatory, anti-oxidant, anti-bacterial, anti-fungal, anti-cancer, leishmanicidal and phytotoxicity. Herein, we presented a bibliography of the researches accomplished on the natural products of Curvularia and Bipolaris, which could help in the future prospecting of novel or new analogues of active metabolites from these two genera. |
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Keywords: | Anti-malarial activity Fungicidal activity Leishmanicidal activity Secondary metabolites |
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