Phenotype and gene frequencies of acid phosphatase (s-AcP) in the human parotid saliva

Summary Genetic polymorphism of the human parotid salivary acid phosphatase (s-AcP) in the Japanese population is described. The use of polyacrylamide gel isoelectric focusing electrophoresis with the pH range of 4.0–6.5 enabled us to discern three variant patterns controlled by two codominant alleles at the single autosomal locus. The two alleles were designated s-AcP: A and s-AcP:a, and the gene frequencies calculated from 183 Japanese subjects were s-AcP:A=0.2268±0.022, s-AcP:a=0.7732±0.022, respectively. The distribution of phenotypes fitted the Hardy-Weinberg equilibrium.