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Key role of clathrin-mediated endocytosis in synaptic vesicle recycling |
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| Authors: | Y. Tsytsyura N. Glyvuk M. Krikunova N. Jung V. Haucke J. Klingauf |
| Affiliation: | 1. Max-Planck Institut für Biophysikalische Chemie, Güttingen, Germany 2. Institut für Experimentalphysik, Universit?t Hamburg, Hamburg, Germany 3. Institut für Chemie-Biochemie, Freie Universit?t Berlin, Berlin, Germany |
| Abstract: | Using novel fluorescent markers, virus-induced modulation of amphiphysin 1 expression, and electron microscopy, we demonstrated that clathrin-mediated endocytosis is the main mechanism of synaptic vesicle retrieval; a hypothesis on the role of a fast “kiss-and-run” mechanism has not been supported. Neirofiziologiya/Neurophysiology, Vol. 39, Nos. 4/5, pp. 388–389, July–October, 2007. |
| Keywords: | amphiphysin 1 synaptic vesicle recycling clathrin-mediated endocytosis |
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