Effects of Continuous and Intermittent Magnetic Fields on Oxidative Parameters In vivo |
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Authors: | ?ule Co?kun Barbaros Balabanl? Ay?e Canseven Nesrin Seyhan |
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Institution: | (1) Science and Arts Faculty, Biology Department, Gazi University, 06500 Beşevler, Ankara, Turkey;(2) Medicine Faculty, Biophysics Department, Gazi University, 06500 Beşevler, Ankara, Turkey |
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Abstract: | Continuous and intermittent 50 Hz, 1.5 mT magnetic field with the exposure period of 4 h/day for 4 days was used to investigate
its possible effect on adult guinea pigs. Tissues and plasma specimens were assessed by biochemical parameters. Malondialdehyde
(MDA), glutathione (GSH), nitric oxide (NO) levels and myeloperoxidase activity (MPO) were examined in plasma, liver and brain
tissues. All parameters were determined by spectrophotometer. While intermittent magnetic field was effective on plasma lipid
peroxidation, continuous magnetic field was found to be effective on plasma MPO activity and NO levels. Augmentation of lipid
peroxidation was also observed in liver tissue both intermittent and continuous magnetic field exposures. These results indicate
that both the intermittent and continuous magnetic field exposures affect various tissues in a distinct manner because of
having different tissue antioxidant status and responses. |
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Keywords: | Magnetic field Lipid peroxidation Antioxidant Nitric oxide |
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