Novel C-ring analogues of 20(S)-camptothecin-part-2: synthesis and in vitro cytotoxicity of 5-C-substituted 20(S)-camptothecin analogues. |
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| Authors: | D Subrahmanyam A Venkateswarlu K Venkateswara Rao T V Sastry G Vandana S A Kumar |
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| Institution: | Natural Products Division, Dr. Reddy's Research Foundation, Miyapur, Hyderabad, India. |
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| Abstract: | A series of 5-C-substituted 20(S)-camptothecin analogues were synthesised and evaluated their in vitro anti-cancer activity. Several of these analogues have showed excellent activity against human tumor cell lines. |
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