Cytotoxic and apoptotic activities of novel amino analogues of boswellic acids |
| |
| Authors: | Shah Bhahwal A Kumar Ajay Gupta Pankaj Sharma Madhunika Sethi Vijay K Saxena Ajit K Singh Jaswant Qazi Ghulam N Taneja Subhash C |
| |
| Institution: | Indian Institute of Integrative Medicine (CSIR), Canal Road, Jammu Tawi 180001, India. |
| |
| Abstract: | 4-Amino analogues prepared from beta-boswellic acid and 11-keto-beta-boswellic acid, wherein the carboxyl group in ursane nucleus was replaced by an amino function via Curtius reaction, displayed improved cytotoxicity than the parent molecules. The same molecules also exhibited apoptotic activity by inducing DNA fragmentation. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
